Publications

Full List: Google Scholar; Pub Med

Journal Articles

1. Clark, C. T., Wang, Y., Johnson, D. C., Lee, S. C., & Smith, Q. “Effects of PDMS Culture on Stem Cell Differentiation Towards Definitive Endoderm and Hepatocytes”. Acta Biomaterialia (2025): Link to Paper

2. Faraji, F., Ramirez, S. I., Clubb, L. M., Sato, K., Burghi, V., Hoang, T. S., Officer, A., Anguiano Quiroz, P.Y., Galloway, W.M., Mikulski, Z. and Medetgul-Ernar, K., Marangoni, P., Jones, K. B., Cao, Y., Molinolo, A. A., Kim, K., Sakaguchi, K., Califano III, J. A., Smith, Q., Goren, A., Klein, O. D., Tamayo, P., & Gutkind, J. S. YAP-driven malignant reprogramming of oral epithelial stem cells at single cell resolution. Nature Communications (2025): Link to Paper

3. Keshavarz M., Smith Q. “Gelatin‐Mediated Vascular Self‐Assembly via a YAP‐MMP Signaling Axis.” Advanced Functional Materials (2024): Link to Paper

4. Wang E., Andrade MJ., Smith Q. “Vascularized liver-on-a-chip model to investigate nicotine-induced dysfunction.” Biomicrofluidics (2023): Link to Paper

   • Featured on University of California Engineering: https://www.youtube.com/watch?v=rC9wkrW0Ra8

5. White MJ., Singh T., Wang E., Smith Q., Kutys ML. “Chip’-ing away at morphogenesis–application of organ-on-chip technologies to study tissue morphogenesis.” Journal of Cell Science (2023): Link to Paper

6. Wang Y., Keshavarz M., Barhouse P., Smith, Q. “Strategies for Regenerative Vascular Tissue Engineering.” Advanced Biology (2022): Link to Paper

7. Barhouse PS., Andrade MJ., Smith Q. “Home Away from Home: Bioengineering Advancements to Mimic the Developmental and Adult Stem Cell Niche.” Frontiers in Chemical Engineering (2022). Link to Paper

8. Smith, Q., Bays, J., Li, L., Shareef, H., Chen, C. S., Bhatia, S. N. “Directing Cholangiocyte Morphogenesis in Natural Biomaterial Scaffolds.” Advanced Science (2022): Link to Paper

9.  Pruitt HC., Lewis D., Ciccaglione M., Connor S., Smith Q., Hickey J W., Schneck J P., Gerecht S. “Collagen fiber structure guides 3D motility of cytotoxic T lymphocytes.” Matrix Biology (2020): Link to Paper

10. Smith Q., Macklin B., Chan XY., Jones H., Trempel M., Gerecht S. “Differential HDAC6 activity modulates ciliogenesis and subsequent mechanosensing of endothelial cells derived from pluripotent stem cells.” Cell Reports (2018): Link to Paper

11. Smith Q.*, Rochman N.*, Carmo AM., Vig D., Chan, XY., Sun S., Gerecht, S. “Cytoskeletal tension regulates mesodermal spatial organization and subsequent vascular fate.”  PNAS (2018): Link to Paper

    • Featured on Johns Hopkins Hub: https://hub.jhu.edu/2018/08/16/cellular-pressure-causes-stem-cells-to-differentiate/

12. Smith Q. and Gerecht S. “Extracellular Matrix Regulation of Stem Cell Fate.” Current Stem Cell Reports (2018): Link to Paper

13. Smith Q., Chan XY., Carmo AM., Trempel, M., Saunders M., & Gerecht S. “Compliant substratum guides endothelial commitment from human pluripotent stem cells.”  Science Advances (2017): Link to Paper

14. Smith Q., Stukalin E., Kusuma S., Gerecht, S., Sun, S. “Stochasticity and Spatial Interaction Govern Stem Cell Differentiation Dynamics.” Scientific Reports (2015): Link to Paper

15. Kusuma S., Smith Q., Facklam A., Gerecht S. “Micropattern size-dependent endothelial differentiation from human pluripotent stem cells.” Journal of Tissue Engineering and Regenerative Medicine (2014): Link to Paper

16. Smith Q. and Gerecht S. “Going with the flow: microfluidic platforms in vascular tissue engineering.” Current Opinion in Chemical Engineering (2014): Link to Paper

17. Hielscher A., Qiu C., Porterfield J., Smith Q., Gerecht S. “Hypoxia Affects the Structure of Breast Cancer Cell-Derived Matrix to Support Angiogenic Responses of Endothelial Cells.” Journal of Carcinogenesis and Mutagenesis (2013): Link to Paper

18. Abaci HE., Devendra R., Smith Q., Gerecht S., Drazer G. “Design and development of microbioreactors for long-term cell culture in controlled oxygen microenvironments.” Biomedical Microdevices (2011): Link to Paper

Book Chapters and Editorials

1. McCray TN., Smith Q, Stevens KR. Can’t touch this: Stromal-mediated ductal proliferation. Cell Stem Cell. 2021; 28(11), 1885-1887.

2. Smith Q, McKinley KL, Chan CJ, Sikandar S, Xiang Y, Passaro D. Introductions to the Community: Early-Career Researchers in the Time of COVID-19. Cell Stem Cell. 2020;27(5):702-4

3. Vo T., Chen AX., Smith Q., Chhabra A., Fleming H., Bhatia S. “Integrated technologies for liver tissue engineering.” The Liver: Biology and Pathobiology (2020)

4. Smith Q., Lowenthal J., Gerecht S. “Mechanotransduction of Cardiovascular Development and Regeneration.” Physics of Blood Flow (2020)

5. Smith Q., Blatchley MR., Gerecht S. “Engineering Niches for Blood Vessel Regeneration. Biology and Engineering of Stem Cell Niches.” Vishwakarma Karp (Eds). Elsevier (2017)

6. Smith Q. and Gerecht S. “Stem Cell Fate Is a Touchy Subject.” Cell Stem Cell (2016)

7. Barreto-Ortiz SF, Smith Q., Gerecht S. “Vascular Development and Morphogenesis in Biomaterials” Vascularization: Regenerative Medicine and Tissue Engineering. Eric Brey (Ed) CRC Press; (2014)

Patents

1. Gerecht S, Chan XY, Smith Q, Shen Y. Three-dimensional vascular network assembly from induced pluripotent stem cells. 2018.